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Importance of voltage-dependent inactivation in N-type calcium channel regulation by G-proteins
Direct regulation of N-type calcium channels by G-proteins is essential to control neuronal excitability and neurotransmitter release. Binding of the G(βγ) dimer directly onto the channel is characterized by a marked current inhibition (“ON” effect), whereas the pore opening- and time-dependent diss...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2703660/ https://ncbi.nlm.nih.gov/pubmed/17171365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-006-0184-0 |
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