Importance of voltage-dependent inactivation in N-type calcium channel regulation by G-proteins

Direct regulation of N-type calcium channels by G-proteins is essential to control neuronal excitability and neurotransmitter release. Binding of the G(βγ) dimer directly onto the channel is characterized by a marked current inhibition (“ON” effect), whereas the pore opening- and time-dependent diss...

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Bibliographic Details
Main Authors: Weiss, Norbert, Tadmouri, Abir, Mikati, Mohamad, Ronjat, Michel, De Waard, Michel
Format: Artigo
Language:Inglês
Published: Springer 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703660/
https://ncbi.nlm.nih.gov/pubmed/17171365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-006-0184-0
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