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Pharmacochaperone-Mediated Rescue of Calcium-Sensing Receptor Loss-of-Function Mutants
The calcium sensing receptor (CaSR) is a Family C/3 G protein-coupled receptor that translates changes in extracellular Ca(2+) into diverse intracellular signals. Loss-of-function mutations in human CaSR cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. CaSR must na...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Endocrine Society
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2703600/ https://ncbi.nlm.nih.gov/pubmed/19389809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0041 |
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