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Smad ubiquitination regulatory factor-2 in the fibrotic kidney: regulation, target specificity and functional implication
Smad ubiquitination regulatory factor-2 (Smurf2) is an E3 ubiqutin ligase that plays a pivotal role in regulating the TGF-β signaling via selectively targeting key components of Smad pathway for degradation. In this study, we have investigated the regulation of Smurf2 expression, its target specific...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2703490/ https://ncbi.nlm.nih.gov/pubmed/18353873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00323.2007 |
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