Neuroprotection by the NR3A Subunit of the NMDA Receptor

Hyperactivation of NMDA-type glutamate receptors (NMDARs) results in excitotoxicity, contributing to damage in stroke and neurodegenerative disorders. NMDARs are generally comprised of NR1/NR2 subunits but may contain modulatory NR3 subunits. Inclusion of NR3 subunits reduces the amplitude and drama...

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Autors principals: Nakanishi, Nobuki, Tu, Shichun, Shin, Yeonsook, Cui, Jiankun, Kurokawa, Toru, Zhang, Dongxian, Chen, H.-S. Vincent, Tong, Gary, Lipton, Stuart A.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2009
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703294/
https://ncbi.nlm.nih.gov/pubmed/19386922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1067-09.2009
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