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PTEN enhances TNF-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway in human glioma Cells
The PTEN tumor suppressor gene modulates cell growth and survival known to be regulated by the activation of the transcription factor NF-κB, suggesting PTEN might affect the NF-κB activation pathway. We found that PTEN inhibited NF-κB activation induced by TNF. The suppression of NF-κB activation co...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2703012/ https://ncbi.nlm.nih.gov/pubmed/17011514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.09.077 |
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