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Mapping Genes Responsible for Strain-specific Iron Phenotypes in Murine Chromosome Substitution Strains
The highly variable clinical phenotype observed in patients homozygous for the C282Y mutation of the hereditary hemochromatosis gene (HFE) is likely due to the influence of non-HFE modifier genes. The primary functional abnormality causing iron overload in hemochromatosis is hyper-absorption of diet...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2703004/ https://ncbi.nlm.nih.gov/pubmed/17493847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2007.03.007 |
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