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Statin Inhibits Kainic Acid-Induced Seizure and Associated Inflammation and Hippocampal Cell Death
Statins are inhibitors of HMG-CoA reductase that have been recently recognized as anti-inflammatory and neuroprotective drugs. Herein, we investigated anti-excitotoxic and anti-seizure effects of statins by using kainic acid (KA)-rat seizure model, an animal model for temporal lobe epilepsy and exci...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2702849/ https://ncbi.nlm.nih.gov/pubmed/18583044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.05.112 |
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