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Statin Inhibits Kainic Acid-Induced Seizure and Associated Inflammation and Hippocampal Cell Death

Statins are inhibitors of HMG-CoA reductase that have been recently recognized as anti-inflammatory and neuroprotective drugs. Herein, we investigated anti-excitotoxic and anti-seizure effects of statins by using kainic acid (KA)-rat seizure model, an animal model for temporal lobe epilepsy and exci...

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Bibliografische gegevens
Hoofdauteurs: Lee, Jin-Koo, Won, Je-Seong, Singh, Avtar K., Singh, Inderjit
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702849/
https://ncbi.nlm.nih.gov/pubmed/18583044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.05.112
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