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Evidence for the Concerted Evolution between Short Linear Protein Motifs and Their Flanking Regions

BACKGROUND: Linear motifs are short modules of protein sequences that play a crucial role in mediating and regulating many protein–protein interactions. The function of linear motifs strongly depends on the context, e.g. functional instances mainly occur inside flexible regions that are accessible f...

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Autori principali: Chica, Claudia, Diella, Francesca, Gibson, Toby J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702822/
https://ncbi.nlm.nih.gov/pubmed/19584925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006052
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