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A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences

BACKGROUND: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and short linear motifs. The latter are involved in protein interactions and formation of regulatory complexes. The function...

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Detalhes bibliográficos
Main Authors: Chica, Claudia, Labarga, Alberto, Gould, Cathryn M, López, Rodrigo, Gibson, Toby J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396637/
https://ncbi.nlm.nih.gov/pubmed/18460207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-229
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