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In the light of directed evolution: Pathways of adaptive protein evolution
Directed evolution is a widely-used engineering strategy for improving the stabilities or biochemical functions of proteins by repeated rounds of mutation and selection. These experiments offer empirical lessons about how proteins evolve in the face of clearly-defined laboratory selection pressures....
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2702793/ https://ncbi.nlm.nih.gov/pubmed/19528653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901522106 |
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