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DNA damage responses in Drosophila nbs mutants with reduced or altered NBS function
The MRN complex, composed of MRE11, RAD50 and NBS, plays important roles in responding to DNA double-strand breaks (DSBs). In metazoans, functional studies of genes encoding these proteins have been challenging because complete loss-of-function mutations are lethal at the organismal level and becaus...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2702778/ https://ncbi.nlm.nih.gov/pubmed/19395318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.03.004 |
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