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DNA damage responses in Drosophila nbs mutants with reduced or altered NBS function

The MRN complex, composed of MRE11, RAD50 and NBS, plays important roles in responding to DNA double-strand breaks (DSBs). In metazoans, functional studies of genes encoding these proteins have been challenging because complete loss-of-function mutations are lethal at the organismal level and becaus...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Mukherjee, Sushmita, LaFave, Matthew C., Sekelsky, Jeff
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702778/
https://ncbi.nlm.nih.gov/pubmed/19395318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.03.004
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