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EXPRESSION AND CHARACTERIZATION OF MUTATIONS IN HUMAN VERY LONG-CHAIN ACYL-COA DEHYDROGENASE USING A PROKARYOTIC SYSTEM

Very long-chain acyl-CoA dehydrogenase (VLCAD) catalyzes the first enzymatic step in the mitochondrial beta-oxidation of fatty acids 14 to 20 carbons in length. More than 100 cases of VLCAD deficiency have been reported with the disease varying from a severe, often fatal neonatal form to a mild adul...

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Detalhes bibliográficos
Main Authors: Goetzman, Eric S., Wang, Yudong, He, Miao, Mohsen, Al-Walid, Ninness, Brittani K., Vockley, Jerry
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702680/
https://ncbi.nlm.nih.gov/pubmed/17374501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2007.01.013
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