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GFAP and its role in Alexander Disease
Here we review how GFAP mutations cause Alexander disease. The current data suggest that a combination of events cause the disease. These include: i) the accumulation of GFAP and the formation of characteristic aggregates, called Rosenthal fibres, ii) the sequestration of the protein chaperones αB-c...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2702672/ https://ncbi.nlm.nih.gov/pubmed/17498694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.04.004 |
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