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GFAP and its role in Alexander Disease

Here we review how GFAP mutations cause Alexander disease. The current data suggest that a combination of events cause the disease. These include: i) the accumulation of GFAP and the formation of characteristic aggregates, called Rosenthal fibres, ii) the sequestration of the protein chaperones αB-c...

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Autores principales: Quinlan, Roy A, Brenner, Michael, Goldman, James E., Messing, Albee
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702672/
https://ncbi.nlm.nih.gov/pubmed/17498694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.04.004
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