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Fluorination of Mammalian Cell Surfaces via the Sialic Acid Biosynthetic Pathway

Metabolic oligosaccharide engineering has been employed to introduce fluorine-containing groups onto mammalian cell surfaces. Incubation of HeLa, Jurkat, and HL60 cells in culture with fluorinated sialic acid and mannosamine analogues resulted in cell-surface presentation of fluorinated glycans. Met...

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Detalhes bibliográficos
Main Authors: Dafik, Laila, d’Alarcao, Marc, Kumar, Krishna
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702668/
https://ncbi.nlm.nih.gov/pubmed/18819798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.09.010
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