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Just Say No to ATOH: How HIC1 Methylation Might Predispose Medulloblastoma to Lineage Addiction
Hypermethylated in cancer-1 (HIC1) is a tumor suppressor frequently targeted for promoter hypermethylation in medulloblastoma, an embryonal tumor of the cerebellum. Recently, we showed that HIC1 is a direct transcriptional repressor of ATOH1, a proneural transcription factor required for normal cere...
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| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2008
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2702666/ https://ncbi.nlm.nih.gov/pubmed/18974104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1904 |
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