Efficacy, Safety, and Potential Biomarkers of Sunitinib Monotherapy in Advanced Hepatocellular Carcinoma: A Phase II Study

PURPOSE: To assess the safety and efficacy of sunitinib in patients with advanced hepatocellular carcinoma (HCC) and explore biomarkers for sunitinib response. PATIENTS AND METHODS: We conducted a multidisciplinary phase II study of sunitinib, an antivascular endothelial growth factor receptor tyros...

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Autori principali: Zhu, Andrew X., Sahani, Dushyant V., Duda, Dan G., di Tomaso, Emmanuelle, Ancukiewicz, Marek, Catalano, Onofrio A., Sindhwani, Vivek, Blaszkowsky, Lawrence S., Yoon, Sam S., Lahdenranta, Johanna, Bhargava, Pankaj, Meyerhardt, Jeffrey, Clark, Jeffrey W., Kwak, Eunice L., Hezel, Aram F., Miksad, Rebecca, Abrams, Thomas A., Enzinger, Peter C., Fuchs, Charles S., Ryan, David P., Jain, Rakesh K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2009
Soggetti:
Original Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702235/
https://ncbi.nlm.nih.gov/pubmed/19470923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.20.9908
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