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CED-10/Rac1 mediates axon guidance by regulating the asymmetric distribution of MIG-10/lamellipodin

Axon migrations are guided by extracellular cues that induce asymmetric outgrowth activity in the growth cone [1, 2]. Several intracellular signaling proteins have been implicated in the guidance response [3–10]. However, how these proteins interact to generate asymmetric outgrowth activity is unkno...

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Detalhes bibliográficos
Main Authors: Quinn, Christopher C., Pfeil, Douglas S., Wadsworth, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702229/
https://ncbi.nlm.nih.gov/pubmed/18499456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.04.050
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