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A mathematical model for human nucleotide excision repair: damage recognition by random order assembly and kinetic proofreading
A mathematical model of human nucleotide excision repair was constructed and validated. The model incorporates cooperative damage recognition by RPA, XPA, and XPC followed by three kinetic proofreading steps by the TFIIH transcription/repair factor. The model yields results consistent with experimen...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2702209/ https://ncbi.nlm.nih.gov/pubmed/17869273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2007.07.025 |
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