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A mathematical model for human nucleotide excision repair: damage recognition by random order assembly and kinetic proofreading

A mathematical model of human nucleotide excision repair was constructed and validated. The model incorporates cooperative damage recognition by RPA, XPA, and XPC followed by three kinetic proofreading steps by the TFIIH transcription/repair factor. The model yields results consistent with experimen...

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Bibliografische gegevens
Hoofdauteurs: Kesseler, Kevin J., Kaufmann, William K., Reardon, Joyce T., Elston, Timothy, Sancar, Aziz
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702209/
https://ncbi.nlm.nih.gov/pubmed/17869273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2007.07.025
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