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A novel mechanism of hippocampal LTD involving muscarinic receptor-triggered interactions between AMPARs, GRIP and liprin-α

BACKGROUND: Long-term depression (LTD) in the hippocampus can be induced by activation of different types of G-protein coupled receptors, in particular metabotropic glutamate receptors (mGluRs) and muscarinic acethycholine receptors (mAChRs). Since mGluRs and mAChRs activate the same G-proteins and...

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Autors principals: Dickinson, Bryony A, Jo, Jihoon, Seok, Heon, Son, Gi Hoon, Whitcomb, Daniel J, Davies, Ceri H, Sheng, Morgan, Collingridge, Graham L, Cho, Kwangwook
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701934/
https://ncbi.nlm.nih.gov/pubmed/19534762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-2-18
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