Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a

BACKGROUND: Since the V617F mutation in JAK2 may not be the initiating event in myeloprofilerative disorders (MPDs) we compared molecular changes in neutrophils from patients with polycythemia vera (PV) and essential thrombocythosis (ET), to neutrophils stimulated by G-CSF administration and to norm...

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Autori principali: Slezak, Stefanie, Jin, Ping, Caruccio, Lorraine, Ren, Jiaqiang, Bennett, Michael, Zia, Nausheen, Adams, Sharon, Wang, Ena, Ascensao, Joao, Schechter, Geraldine, Stroncek, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701925/
https://ncbi.nlm.nih.gov/pubmed/19497108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-7-39
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