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Transcriptional Anti-repression: THYROID HORMONE RECEPTOR β-2 RECRUITS SMRT COREPRESSOR BUT INTERFERES WITH SUBSEQUENT ASSEMBLY OF A FUNCTIONAL COREPRESSOR COMPLEX

Thyroid hormone receptors (T3Rs) are hormone-regulated transcription factors. Different T3R isoforms are expressed in a tissue-specific and developmentally regulated manner. The T3Rα-1, β-0, and β-1 isoforms typically repress target gene expression in the absence of hormone and activate transcriptio...

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Autori principali: Yang, Zhihong, Hong, Suk-Hyun, Privalsky, Martin L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701910/
https://ncbi.nlm.nih.gov/pubmed/10601274
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