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Thyroid hormone receptors mutated in liver cancer function as distorted antimorphs

Aberrant thyroid hormone receptors (TRs) are found in over 70% of the human hepatocellular carcinomas (HCCs) analysed. To better understand the role(s) of these TR mutants in this neoplasia, we analysed a panel of HCC mutant receptors for their molecular properties. Virtually all HCC-associated TR m...

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Detalhes bibliográficos
Main Authors: Chan, IH, Privalsky, ML
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701908/
https://ncbi.nlm.nih.gov/pubmed/16434963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209389
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