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Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility

Epidermolysis bullosa (EB) simplex is a rare genetic condition typified by superficial bullous lesions that result from frictional trauma to the skin. Most cases are due to dominantly acting mutations in either keratin 14 (K14) or K5, the type I and II intermediate filament (IF) proteins tasked with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Coulombe, Pierre A., Kerns, Michelle L., Fuchs, Elaine
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701872/
https://ncbi.nlm.nih.gov/pubmed/19587453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38177
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