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Laminopathies and the long strange trip from basic cell biology to therapy

The main function of the nuclear lamina, an intermediate filament meshwork lying primarily beneath the inner nuclear membrane, is to provide structural scaffolding for the cell nucleus. However, the lamina also serves other functions, such as having a role in chromatin organization, connecting the n...

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Dades bibliogràfiques
Autors principals: Worman, Howard J., Fong, Loren G., Muchir, Antoine, Young, Stephen G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701866/
https://ncbi.nlm.nih.gov/pubmed/19587457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37679
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