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Inhibition of Apoptosis-Regulated Signaling Kinase-1 and Prevention of Congestive Heart Failure by Estrogen

BACKGROUND: Epidemiological studies have shown gender differences in the incidence of congestive heart failure (CHF); however, the role of estrogen in CHF is not known. We hypothesize that estrogen prevents cardiomyocyte apoptosis and the development of CHF. METHODS AND RESULTS: 17β-Estradiol (E2, 0...

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Detalhes bibliográficos
Main Authors: Satoh, Minoru, Matter, Christian M., Ogita, Hisakazu, Takeshita, Kyosuke, Wang, Chao-Yung, Dorn, Gerald W., Liao, James K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701741/
https://ncbi.nlm.nih.gov/pubmed/17562954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.106.657981
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