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Requirement of Rac1 in the development of cardiac hypertrophy

The development of cardiac hypertrophy is mediated, in part, by increase in NADPH oxidase activity and myocardial oxidative stress. The Rho GTPase, Rac, regulates NADPH oxidase activity through interaction with gp91(phox) and p67(phox) (in which “phox” is phagocyte oxidase). However, it is not known...

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Autors principals: Satoh, Minoru, Ogita, Hisakazu, Takeshita, Kyosuke, Mukai, Yasushi, Kwiatkowski, David J., Liao, James K.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1455410/
https://ncbi.nlm.nih.gov/pubmed/16651530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510444103
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