Congenital DNA repair deficiency results in protection against renal ischemia reperfusion injury in mice

Cockayne syndrome and other segmental progerias with inborn defects in DNA repair mechanisms are thought to be due in part to hypersensitivity to endogenous oxidative DNA damage. The accelerated aging-like symptoms of this disorder include dysmyelination within the central nervous system, progressiv...

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Hauptverfasser: Susa, Denis, Mitchell, James R., Verweij, Marielle, van de Ven, Marieke, Roest, Henk, van den Engel, Sandra, Bajema, Ingeborg, Mangundap, Kirsten, IJzermans, Jan N. M., Hoeijmakers, Jan H. J., de Bruin, Ron W. F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701740/
https://ncbi.nlm.nih.gov/pubmed/19338497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2009.00463.x
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