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Anatomy of the E2 ligase fold: implications for enzymology and evolution of ubiquitin/Ub-like protein conjugation

The configuration of the active site of E2 ligases, central enzymes in the ubiquitin/ubiquitin-like protein (Ub/Ubl) conjugation systems, has long puzzled researchers. Taking advantage of the wealth of newly available structures and sequences of E2s from diverse organisms, we performed a large-scale...

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Bibliografiset tiedot
Päätekijät: Burroughs, A. Maxwell, Jaffee, Marcie, Iyer, Lakshminarayan M., Aravind, L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701696/
https://ncbi.nlm.nih.gov/pubmed/18276160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2007.12.006
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