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Comparison of the Efficacy of two Anticonvulsants, Phenytoin and Valproate to Improve PCP and d-amphetamine Induced Deficits in a Reversal Learning Task in the Rat

Recent studies in our laboratory have shown that PCP (phencyclidine) and d-amphetamine induce a cognitive deficit in rats, in a paradigm of potential relevance for the pathology of schizophrenia. Atypical, but not classical antipsychotics and the anticonvulsant, lamotrigine have been shown to preven...

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Detalhes bibliográficos
Main Authors: Idris, Nagi F., Neill, Jo C., Large, Charles H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701680/
https://ncbi.nlm.nih.gov/pubmed/19562089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/neuro.08.008.2009
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