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Comparative double blind clinical trial of phenytoin and sodium valproate as anticonvulsant prophylaxis after craniotomy: efficacy, tolerability, and cognitive effects

OBJECTIVE—To determine the efficacy, tolerability, and impact on quality of life and cognitive functioning of anticonvulsant prophylaxis with phenytoin or sodium valproate in patients after craniotomy.
METHODS—A prospective, stratified, randomised, double blind single centre clinical trial was perfo...

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Detalhes bibliográficos
Main Authors: Beenen, L, Lindeboom, J, Trenite, D, Heimans, J, Snoek, F, Touw, D, Ader, H, van Alphen, H A M
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1736591/
https://ncbi.nlm.nih.gov/pubmed/10486394
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