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Sensing Pathogens and Danger Signals by the Inflammasome

The NLR (nucleotide-binding domain leucine-rich repeat containing) family of intracellular sensors is a critical component of the innate immune system. A number of NLR family members can form multiprotein complexes, called inflammasomes, and are capable of activating the cysteine protease caspase-1...

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Bibliografiske detaljer
Main Authors: Pedra, Joao H. F., Cassel, Suzanne L., Sutterwala, Fayyaz S.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701640/
https://ncbi.nlm.nih.gov/pubmed/19223160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2009.01.006
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