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An integrated comparative phosphoproteomic and bioinformatic approach reveals a novel class of MPM-2 motifs upregulated in EGFRvIII-expressing glioblastoma cells

Glioblastoma (GBM, WHO grade IV) is an aggressively proliferative and invasive brain tumor that carries a poor clinical prognosis with a median survival of 9 to 12 months. In a prior phosphoproteomic study performed in the U87MG glioblastoma cell line, we identified tyrosine phosphorylation events t...

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Main Authors: Joughin, Brian A., Naegle, Kristen M., Huang, Paul H., Yaffe, Michael B., Lauffenburger, Douglas A., White, Forest M.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701618/
https://ncbi.nlm.nih.gov/pubmed/19081932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b815075c
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