The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

Activated oncogenic signaling is central to the development of nearly all forms of cancer, including the most common class of primary brain tumor, glioma. Research over the last two decades has revealed the particular importance of the Akt pathway, and its molecular antagonist PTEN (phosphatase and...

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Detalhes bibliográficos
Main Authors: Huse, Jason T., Brennan, Cameron, Hambardzumyan, Dolores, Wee, Boyoung, Pena, John, Rouhanifard, Sara H., Sohn-Lee, Cherin, le Sage, Carlos, Agami, Reuven, Tuschl, Thomas, Holland, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701585/
https://ncbi.nlm.nih.gov/pubmed/19487573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1777409
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