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Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression
BACKGROUND: Drosophila Groucho and its human Transducin-like-Enhancer of Split orthologs (TLEs) function as transcription co-repressors within the context of Wnt signaling, a pathway with strong links to cancer. The current model for how Groucho/TLE's modify Wnt signaling is by direct competiti...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701438/ https://ncbi.nlm.nih.gov/pubmed/19460168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-159 |
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