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Specific engagement of TLR4 or TLR3 does not lead to IFN-β-mediated innate signal amplification and STAT1 phosphorylation in resident murine alveolar macrophages

The innate immune response must be mobilized promptly yet judiciously via Toll-like receptors (TLRs) to protect the lungs against pathogens. Stimulation of murine peritoneal macrophage (PMø) TLR4 or TLR3 by pathogen-associated molecular patterns (PAMPs) typically induces type I interferon β (IFN-β),...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Punturieri, Antonello, Alviani, Rebecca S., Polak, Timothy, Copper, Phil, Sonstein, Joanne, Curtis, Jeffrey L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701405/
https://ncbi.nlm.nih.gov/pubmed/15240691
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