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Specific engagement of TLR4 or TLR3 does not lead to IFN-β-mediated innate signal amplification and STAT1 phosphorylation in resident murine alveolar macrophages
The innate immune response must be mobilized promptly yet judiciously via Toll-like receptors (TLRs) to protect the lungs against pathogens. Stimulation of murine peritoneal macrophage (PMø) TLR4 or TLR3 by pathogen-associated molecular patterns (PAMPs) typically induces type I interferon β (IFN-β),...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701405/ https://ncbi.nlm.nih.gov/pubmed/15240691 |
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