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CYTOTOXIC PHOSPHOLIPID OXIDATION PRODUCTS: CELL DEATH FROM MITOCHONDRIAL DAMAGE AND THE INTRINSIC CASPASE CASCADE*

Phospholipid oxidation products accumulate in the necrotic core of atherosclerotic lesions, in apoptotic cells, and circulate in oxidized LDL. Phospholipid oxidation generates toxic products, but little is known about which specific products are cytotoxic, their receptors, or the mechanism(s) that i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Rui, Yang, Lili, McIntyre, Thomas M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701377/
https://ncbi.nlm.nih.gov/pubmed/17597068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M702865200
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