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Matrix metalloproteinase-9 inhibition ameliorates pathogenesis and improves skeletal muscle regeneration in muscular dystrophy

Duchenne muscular dystrophy (DMD) is a fatal X-linked genetic disorder of skeletal muscle caused by mutation in dystrophin gene. Although the degradation of skeletal muscle extracellular matrix, inflammation and fibrosis are the common pathological features in DMD, the underlying mechanisms remain p...

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Hlavní autoři: Li, Hong, Mittal, Ashwani, Makonchuk, Denys Y., Bhatnagar, Shephali, Kumar, Ashok
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701330/
https://ncbi.nlm.nih.gov/pubmed/19401296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp191
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