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Matrix metalloproteinase-9 inhibition ameliorates pathogenesis and improves skeletal muscle regeneration in muscular dystrophy

Duchenne muscular dystrophy (DMD) is a fatal X-linked genetic disorder of skeletal muscle caused by mutation in dystrophin gene. Although the degradation of skeletal muscle extracellular matrix, inflammation and fibrosis are the common pathological features in DMD, the underlying mechanisms remain p...

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Bibliographic Details
Main Authors: Li, Hong, Mittal, Ashwani, Makonchuk, Denys Y., Bhatnagar, Shephali, Kumar, Ashok
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701330/
https://ncbi.nlm.nih.gov/pubmed/19401296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp191
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