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The Severity of Retinal Degeneration in Rp1h Gene-Targeted Mice Is Dependent on Genetic Background

PURPOSE: The severity of disease in patients with retinitis pigmentosa (RP) can vary significantly, even among patients with the same primary mutations. It is hypothesized that modifier genes play important roles in determining the severity of RP, including the retinitis pigmentosa 1 (RP1) form of d...

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Autori principali: Liu, Qin, Saveliev, Alexei, Pierce, Eric A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701263/
https://ncbi.nlm.nih.gov/pubmed/19060274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2776
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