Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates

BACKGROUND: CB(1) cannabinoid receptors in the brain are known to participate in the regulation of reward-based behaviors, however, the contribution of each of the endocannabinoid transmitters, anandamide and 2-arachidonoylglycerol (2-AG), to these behaviors remains undefined. To address this questi...

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Detalhes bibliográficos
Main Authors: Justinova, Zuzana, Mangieri, Regina A., Bortolato, Marco, Chefer, Svetlana I., Mukhin, Alexey G., Clapper, Jason R., King, Alvin R., Redhi, Godfrey H., Yasar, Sevil, Piomelli, Daniele, Goldberg, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701259/
https://ncbi.nlm.nih.gov/pubmed/18814866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2008.08.008
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