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The Role of Akt/GSK-3β Signaling in Familial Hypertrophic Cardiomyopathy

Mutations in cardiac troponin T (TnT) are a cause of familial hypertrophic cardiomyopathy (FHC). Transgenic mice expressing a missense mutation (R92Q) or a splice site donor mutation (Trunc) in the cardiac TnT gene have mutation-specific phenotypes but mice of both models have smaller hearts compare...

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Detalhes bibliográficos
Main Authors: Luckey, Stephen W., Walker, Lori A., Smyth, Tyson, Mansoori, Jason, Messmer-Kratzsch, Antke, Rosenzweig, Anthony, Olson, Eric, Leinwand, Leslie
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701230/
https://ncbi.nlm.nih.gov/pubmed/19233194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.02.010
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