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Catalytic Properties of Botulinum Neurotoxins Subtypes A3 and A4
Botulinum toxins (BoNT) are zinc proteases (serotypes A-G) which cause flaccid paralysis through the cleavage of SNARE proteins within motor neurons. BoNT/A was originally organized into two subtypes: BoNT/A1 and BoNT/A2, which are ~ 95 % homologous and possess similar catalytic activities. Subseque...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701208/ https://ncbi.nlm.nih.gov/pubmed/19256469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801686b |
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