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Two-stage folding of HP-35 from ab initio simulations

Accurate ab initio simulation of protein folding is a critical step toward elucidation of protein folding mechanisms. In this report, we demonstrate highly accurate folding of the 35-residue villin headpiece subdomain (HP35) by all-atom molecular dynamics simulations using AMBER ff03 and the general...

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Détails bibliographiques
Auteurs principaux: Lei, Hongxing, Duan, Yong
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701201/
https://ncbi.nlm.nih.gov/pubmed/17512537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.04.040
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