Llwytho...
The fast-folding HP35 double mutant has a substantially reduced primary folding free energy barrier
The LYS24∕29NLE double mutant of villin headpiece subdomain (HP35) is the fastest folding protein known so far with a folding time constant of 0.6 μs. In this work, the folding mechanism of the mutant has been investigated by both conventional and replica exchange molecular dynamics (CMD and REMD) s...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Institute of Physics
2008
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2671186/ https://ncbi.nlm.nih.gov/pubmed/19045234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.2995987 |
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